Skin aging is a multifactorial process consisting of two distinct and independent mechanisms: intrinsic and extrinsic aging. Youthful skin retains its turgor, resilience and pliability, among others, due to its high content of water. Daily external injury, in addition to the normal process of aging, causes loss of moisture. The key molecule involved in skin moisture is hyaluronic acid (HA) that has unique capacity in retaining water. There are multiple sites for the control of HA synthesis, deposition, cell and protein association and degradation, reflecting the complexity of HA metabolism. The enzymes that synthesize or catabolize HA and HA receptors responsible for many of the functions of HA are all multigene families with distinct patterns of tissue expression. Understanding the metabolism of HA in the different layers of the skin and the interactions of HA with other skin components will facilitate the ability to modulate skin moisture in a rational manner.
The function of the skin as a barrier is partly attributed to the lamellar bodies, thought to be modified lysosomes containing hydrolytic enzymes. They fuse with the plasma membranes of mature keratinocytes and they have the ability to acidify via proton pumps and partially convert their polar lipids into neutral lipids. Diffusion of aqueous material through the epidermis is blocked by these lipids synthesized by keratinocytes in the stratum granulosum. This boundary effect corresponds to the level of HA staining. The HA-rich area inferior to this layer may obtain water from the moisture-rich dermis, and the water contained therein cannot penetrate beyond the lipid-rich stratum granulosum. The hydration of the skin critically depends on the HA-bound water in the dermis and in the vital area of the epidermis, while maintenance of hydration essentially depends on the stratum granulosum. Extensive loss of the stratum granulosum in patients with burns may cause serious clinical problems due to dehydration.
Human skin aging is a complex biological process, not yet fully understood. It is the result of two biologically independent processes. The first is intrinsic or innate aging, an unpreventable process, which affects the skin in the same pattern as it affects all internal organs. The second is extrinsic aging, which is the result of exposure to external factors, mainly ultraviolet (UV) irradiation, that is also referred to as photoaging.1 Intrinsic skin aging is influenced by hormonal changes that occur with age,2 such as the gradual decreased production of sex hormones from the mid-twenties and the diminution of estrogens and progesterone associated with menopause. It is well established that the deficiency in estrogens and androgens results in collagen degradation, dryness, loss of elasticity, epidermal atrophy and wrinkling of the skin.
Skin aging is also associated with loss of skin moisture. The key molecule involved in skin moisture is hyaluronan or hyaluronic acid (HA), a glycosaminoglycan (GAG) with a unique capacity to bind and retain water molecules.6 HA belongs to the extracellular matrix (ECM) molecules. During the past decades the constituents of the skin have been well characterized. In the beginning, most of the studies focused on the cells that comprise the skin layers, such as the epidermis, the dermis and the underlying subcutis. Recently, it is appreciated that ECM molecules that lie between cells, in addition to providing a constructive framework, they exert major effects on cellular function. These ECM molecules, although they appear amorphous by light microscopy, they form a highly organized structure, comprising mainly of GAG, proteoglycans, growth factors and structural proteins such as collagens. Yet, the predominant component of the skin ECM is HA.
I'm Fabulous Hyaluronic Protein is formulated 10 times more potent than any other topical compound with the same name. This product mimics the skin's own natural protein and binds to the skin the same way.
Bio-Identical Hyaluronic Protein is bio-identical and can be compressed into the skin and absorbed as deep as 1 full micron of topical penetration. Bio-Identical compounding is a brand new technology where the topical compound can be metabolized by the skin tissue rather than creating chemical dependency.
Created with low molecular weight for super deeper penetration! Bio-Identical Hyaluronic Protein contains no poly or methylparaben preservatives and is bottled every 7 days which gives it more than 12 months of shelf life.
How to use: For best results, this product should be used on new skin growth.
The key to flawless skin is rapid exfoliation followed by infusion of protein!
I'm Fabulous Hyaluronic Acid may also be used in spot treatment applications.
This serum is very potent
This product is compounded from NASHA GRADE Hyaluronic Acid which is the key active ingredient. This product contains no preservatives or inactive materials.
The key to flawless skin is RAPID EXFOLIATION followed by INFUSION OF PROTEIN.
Our Hyaluronic acid is pure not with other ingredients! Excellent to use with the skin roller as well for deeper penetration especially for scars.
I'm Fabulous HA serum is formulated 10 times more potent than any other topical compound with the same name. This product mimics the skin's own natural protein and binds to the skin the same way. Formulated with a patented LIFT-TECHNOLOGY, I'm Fabulous HA Protein is bio-identical and can be compressed into the skin an absorbed as deep as 1 full micron of topical penetration.
This product is compounded from NASHA GRADE Hyaluronic Acid which is the key active ingredient in the injectable filler called RESTYLANE sold for $600 per cc administered only by trained professionals! This product contains no preservatives or inactive materials. Not for ingestion or injection.
Hyaluronic acid is a protein naturally occurring in the deeper layers (dermis) of human skin. As we age, we lose the Hyaluronic acid in our skin and the wrinkles and other outward signs of aging set it.
Hyaluronic acid has the ability to hold up 1000 times its weight in water making it one of the most effective moisturizers discovered by medical science.
As the best hydrating ingredient on the market, it can lock and absorb the moisture and nutrients in the dermis making your skin healthier, soft and supple.
How to use:
Esthetic compressing technique:
1-Apply a few drops of serum on the area need to be treated or your full face.
2-Leave it for 10 minutes then, fold a clean, damp (NOT wet) paper towel. Press it directly onto the skin for 5 minutes, concentrating on problem areas.
3-Followed by warm moist washcloths for 4-5 minutes per area.
72% certified organic ingredients
Ingredients: Aqua (Water), Hamamelis Virginiana Water (Witch Hazel), Cassia Angustifolia Seed Polysaccharide (botanical hyaluronic acid), Glycerin (Kosher, Vegetable), Aloe Barbadensis Leaf Extract (Organic Aloe), Dimethyl Sulfone (MSM), Tocopheryl Acetate (Vitamin E), Sodium Ascorbyl Phosphate (Vitamin C), Simondsia Chinensis Oil (Organic Jojoba), Pelargonium Graveolens Oil (Geranium Essential Oil), Camellia Sinensis Extract (Organic Green Tea), Centella Asiatica Extract (Organic Gotu Kola), Equisetum Arvense Extract (Horsetail), Taraxacum Officinale Extract (Dandelion), Geranium Maculatum Extract (Wild Geranium), Leuconostoc/Radish Root Ferment Filtrate.
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